The Bartolomucci Lab, at the Department of Integrative Biology and Physiology, University of Minnesota, primarily focuses on the molecular mechanisms of obesity and stress-induced pathologies.
We use an integrative approach to animal patho-physiology which combines state-of-the-art in vivo models with cellular models and molecular techniques. Great emphasis is devoted to the face and construct validity of the animal models used for a specific human disease.
Current major ongoing research projects in the Lab are:
Biology and pharmacology of VGF-derived peptides
The mechanisms of anti-obesity and anti-diabetic effects of the VGF-derived peptide TLQP-21
The mechanisms of chronic social stress-induced obesity and type 2 diabetes
The long term consequences of chronic social stress on mortality and ageing